Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion
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چکیده
منابع مشابه
the past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia.
Invadopodia are branched actin-rich structures associated with extracellular matrix (ECM) degradation that collectively form the invasive machinery of aggressive cancer cells. Cortactin is a prominent component and a specific marker of invadopodia. Amplification of cortactin is associated with poor prognosis in head and neck squamous cell carcinomas (HNSCC), possibly because of its activity in ...
متن کاملLaxity in healthy and osteoarthritic knees.
OBJECTIVE Although it is a cause of osteoarthritis (OA) in animal models, laxity in human knee OA has been minimally evaluated. Ligaments become more compliant with age; whether this results in clinical laxity is not clear. In theory, laxity may predispose to OA and/or result from OA. Our goals were to examine the correlation of age and sex with knee laxity in control subjects without OA, compa...
متن کاملJoint Proprioception in Normal and Osteoarthritic Knees
The worldwide increase in the elderly population is the most important change as per the public health statistics for 21st century [1]. It is being estimated that the number of people over the age of 65 will be doubled in the next 20 years [2]. Consequently, osteoarthritis (OA) and similar diseases that are more frequently encountered in advancing years become much more important from both medi...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2015
ISSN: 1063-4584
DOI: 10.1016/j.joca.2015.05.020